Directions for Use Antibiotic therapy is recommended for the initial control of infection or where deep pyoderma exists. Wash dog with Pyohex Medicated Shampoo or other appropriate product and rinse thoroughly. Place a small amount of Pyohex Medicated Conditioner into the palm of the hand, spread evenly over both hands, then gently massage into the coat. Use approximately 1 mL for every kg weight of the dog. Do not rinse after application. Pyohex Medicated Conditioner can be used on haired and nonhaired skin.